QIAGEN 1023537 Bottle Qiazol Lysis Reagent 50

( Brand: Qiagen ), ( Manufacturer Part Number: 1023537 ), ( Country/region Of Manufacture: United States )

Review QIAGEN Sealed Bottle Of Qiazol Lysis Reagent From 50 Ml

The QIAGEN Qiazol Lysis Reagent 50 (Product Code: 1023537) is a versatile and effective reagent designed for efficient lysis and RNA isolation from various types of biological samples, including blood, tissue, and cell cultures. This reagent is a crucial component of the RNeasy Mini Kit and RNeasy Plus Mini Kit for RNA isolation and purification, making it an essential tool for laboratories working with RNA-based research.

The Qiazol Lysis Reagent is a buffered guanidine thiocyanate-based solution, which ensures gentle cell lysis while ensuring the integrity and stability of RNA molecules. Upon contact with cellular or tissue material, the Qiazol reagent rapidly penetrates the cells leading to efficient and fast lysis. It contains a denaturant to denature proteins and a virucidal agent to inactivate viruses, which reduces the risk of carryover contamination during the RNA isolation process.

One major advantage of the Qiazol Lysis Reagent is its ability to provide a single transfer step for RNA isolation. The lysate produced by this reagent can be directly transferred to the RNeasy Mini or RNeasy Plus Mini spin column for RNA binding and purification. This streamlined workflow reduces hands-on time, saves valuable laboratory resources, and provides a higher downstream yield of RNA.

Moreover, the Qiazol Lysis Reagent is compatible with various RNA extraction methods, including the spin column method and the guanidine-isothiocyanate-phenol method. This flexibility allows researchers to choose the most suitable approach based on their sample type and downstream applications.

Additionally, the Qiazol Lysis Reagent is available in various sizes, including 250 mL, 500 mL, and 1 L bulk bottles and pre-aliquoted 50 mL tubes. This extensive range caters to a wide variety of experimental requirements in different research settings, allowing researchers to choose the most convenient and cost-effective option.

In summary, the QIAGEN Qiazol Lysis Reagent 50 (1023537) is a high-performance and versatile reagent that provides a rapid, efficient, and single-step solution for RNA isolation from various biological samples. Its unique features, such as substantial virucidal activity, denaturation of proteins, and compatibility with a range of RNA extraction methods, make it an essential component for laboratories conducting RNA research.

QIAGEN's RNeasy Mini Kit (cat. no. 74104) is a popular total RNA isolation kit from QIAGEN, but you specifically asked about the QIAzol Lysis Reagent (cat. no. 79306), which is often used in conjunction with the RNeasy Mini Kit for RNA isolation from various types of samples, including tough ones like plant or mammalian cell cultures. Here, we'll discuss the pros and cons of buying a bottle (50 mL) of QIAGEN's Qiazol Lysis Reagent (cat. no. 1023537).

1. Highly effective in lysing various types of cells and tissues, providing good RNA yield.

2. Stable at room temperature, making it convenient for use in the laboratory.

3. Can be stored long-term at room temperature without significant loss of efficacy.

4. Compatible with downstream applications such as reverse transcription, cDNA synthesis, and quantitative real-time PCR (qPCR).

5. Easy to use, with a simple method that involves mixing cell lysate with an equal volume of chloroform, followed by phase separation and centrifugation to extract RNA.

1. Qiazol is denser than water, which can pose challenges during pipetting, requiring care to avoid interference with precise measurements.

2. Contains phenol and chloroform, which require special disposal procedures.

3. Might not be cost-effective for small-scale RNA isolation experiments, due to the large volume of the bottle (50 mL).

Qiazol Lysis Reagent (cat. no. 1023537) is a dependable reagent for efficiently lysing various types of cells and tissues for RNA isolation. It offers advantages such as stability, ease of use, and compatibility with downstream applications. However, its density, incompatibility with standard pipetting, and the need for specialized disposal procedures could be considered possible drawbacks. In terms of purchasing a 50 mL bottle, it might not be the most cost-effective option for small-scale experiments. Overall, if you require efficient lysis for RNA isolation, particularly when dealing with difficult samples, and are willing to accommodate the potential challenges of handling this denser reagent, Qiazol Lysis Reagent could be a valuable investment.

Details:

No other accessories or manuals vendor packing material is available. Original vendor box included. Sealed bottle of Qiazol Lysis Reagent from Qiagen 50 ml size catalog number: 1023537. Label of the bottle is partially scratched.

Item is new and sealed by original vendor.

part #: 1023537 price

• $67.00

specifications labequipi:

• brand: Qiagen
• mpn: 1023537
• country/region of manufacture: United States

seller labequipi:

• rating: 100.0%
• # reviews: 1258
• city: Silver Spring, Maryland

general labequipi:

• Healthcare, Lab Dental > Medical Lab Equipment, Devices > Other Medical Lab Equipment
• condition: New

offer labequipi:

• quantity: 1
• availability: In Stock
• sold: 0
• started: January 19, 2025
• options: Ship-to-home

payments labequipi:

• credit card: Discover
• wallet: Apple-pay
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shipping labequipi:

• carrier: USPS
• type: Calculated
• transit: 5-10 Days
• class: Standard
• service: USPS Ground Advantage
• cost: $49.28

returns labequipi:

• policy: No Returns

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