
( Brand: Biacore ), ( Manufacturer Part Number: 22-0471-00 ), ( Model: 22-0512-25 ), ( Part Type: Sensor Board ), ( Unit Type: Unit )
The BIAcore 22-0471-00 Optical Sensor Boards are a crucial component of the BIAcore X PRISM system, a versatile and highly sensitive instrument designed for real-time measurement of biomolecular interactions. These sensor boards are engineered to provide exceptional performance and reliability for researchers working in various fields such as biotechnology, pharmaceuticals, and academia.
Each optical sensor board features a high-density array of 140 sensor spots, which are capable of detecting changes in refractive index as small as 10-7 RIU. This level of sensitivity enables researchers to study a wide range of biomolecular interactions, including protein-protein, protein-ligand, and ligand-carbohydrate interactions, with high precision and accuracy.
The sensor boards are coated with a thin layer of dextran, a naturally occurring carbohydrate polymer, which acts as a matrix for immobilizing biomolecules. Researchers can easily and specifically immobilize their target molecules on the dextran layer using various chemistries, including amine coupling, carboxylate coupling, and biotin-avidin interaction.
The optical sensor boards are designed to be robust and durable, with a long-term storage stability of several years. They are also easy to use, with a simple and intuitive software interface that allows users to control the instrument, design and optimize experiments, and analyze data in real-time.
Moreover, the BIAcore X PRISM system and the optical sensor boards support a wide range of sample types, including buffers, proteins, peptides, and small molecules, making them a versatile tool for researchers working in various fields. The system is also compatible with a range of detection modalities, including SPR, FRET, and UV absorbance, providing researchers with multiple options for detecting and analyzing their biomolecular interactions.
Overall, the BIAcore 22-0471-00 Optical Sensor Boards offer researchers a powerful and versatile tool for studying biomolecular interactions in real-time, with exceptional sensitivity, reliability, and ease of use. Whether you are working on drug discovery, diagnostics, or fundamental research, these sensor boards can help you gain new insights into the complex biomolecular interactions that drive biological processes.
The BIAcore 22-0471-00 optical sensor boards are components used in BIAcore's surface plasmon resonance (SPR) systems for biomolecular interaction analysis. Here are some pros and cons of buying these sensor boards:
Pros:1. High-quality sensors: BIAcore is a leading company in the field of SPR technology, and their sensors are known for their high sensitivity and accuracy.
2. Wide dynamic range: The sensor boards offer a wide dynamic range, allowing for the detection of small binding events as well as large ones.
3. Versatile applications: These sensors can be used for various applications, including protein-protein, protein-ligand, and carbohydrate-ligand interactions.
4. Reusable: The sensor chips can be regenerated and reused, reducing the overall cost per experiment.
5. Real-time analysis: SPR technology offers real-time analysis of binding events, allowing for rapid optimization of experimental conditions.
Cons:1. Expensive: The BIAcore sensor boards are more expensive than other types of sensors, making them a significant investment for researchers.
2. Complex setup: The SPR system and sensor setup can be complex and require specialized training to use effectively.
3. Limited sample volume: The sample volume that can be injected over the sensor chip is limited, which may require careful optimization of experimental conditions.
4. Limited to planar surfaces: The SPR technology is limited to planar surfaces, which may not be suitable for analyzing interactions in complex environments.
In conclusion, the BIAcore 22-0471-00 optical sensor boards offer high-quality sensors with a wide dynamic range and versatile applications. However, they are expensive, complex to set up, and limited to planar surfaces. Researchers considering purchasing these sensors should weigh the pros and cons carefully and determine if the benefits outweigh the costs for their specific research needs.
Recommendation:If researchers require high-sensitivity and accurate analysis of biomolecular interactions, and have the budget and expertise to set up and use a BIAcore SPR system, then the BIAcore 22-0471-00 optical sensor boards are a recommended investment. For researchers with limited budgets or simpler research needs, alternative sensor technologies may be more cost-effective and suitable.
AS-IS items are sold without warranty. Shipping and Handling. 30 Day Return Warranty. Optical Sensor Boards 22-0471-00 from Biacore C.