THERMO SCIENTIFIC 25305-052130 Hypersil Aq Polar Endcapped C18 50X2.1MM Column

( Brand: Thermo Scientific ), ( Manufacturer Part Number: 25305-052130 ), ( Country Of Origin: United States ), ( Intended Use/discipline: Hplc Column )

Review THERMO SCIENTIFIC New Hypersil Gold Aq C18 50x2.1mm Polar Endcapped Column

The Thermo Scientific Hypersil Gold AQ C18 50mm x 2.1mm Polar Endcapped Column is a high-performance analytical reversed-phase chromatography column designed for the separation of both organic and inorganic compounds. This particular column is part of the Hypersil Gold AQ series, which is known for its exceptional chromatographic performance and versatility.

The column features a 50mm length and a 2.1mm inner diameter, making it well-suited for use in high-performance liquid chromatography (HPLC) systems with compact footprints or those requiring high sample throughput. The column is packed with 5-micron-sized Hypersil Gold C18 particles, which are made of gold-standard bonded phase material. The particles are polar endcapped, meaning they have a polar functional group at the end of the stationary phase. This functional group enhances the column's ability to retain and separate polar compounds, making it an ideal choice for applications involving acidic or basic compounds.

The Hypersil Gold AQ C18 column's 1.7-micron pore size allows for efficient mass transfer and rapid analysis, while the 100 pore size distribution ensures a good balance between resolution and efficiency. The column's C18 stationary phase provides excellent retention for a wide range of compounds, making it a popular choice for general-purpose separations.

The Thermo Scientific Hypersil Gold AQ C18 50mm x 2.1mm Polar Endcapped Column is designed to provide excellent reproducibility and robustness, even when separating compounds with challenging properties. The column is suitable for use with a wide range of mobile phases, including water, acetonitrile, methanol, and other common solvents. It can be operated at temperatures ranging from 0 C to 60 C, making it adaptable to various separation requirements.

The column comes with a stainless steel guard column to protect the analytical column from particle contamination and column damage. It also includes a column oven to maintain a consistent column temperature during separation. The Hypersil Gold AQ C18 50mm x 2.1mm Polar Endcapped Column is delivered in a protective sleeve to ensure safe handling and transportation.

In summary, the Thermo Scientific Hypersil Gold AQ C18 50mm x 2.1mm Polar Endcapped Column is a versatile, high-performance HPLC column designed for the separation of polar compounds. Its compact size, efficient mass transfer, and good balance between resolution and efficiency make it an excellent choice for laboratories requiring high sample throughput or those working on challenging separations.

The Thermo Scientific Hypersil Gold AQ C18 50x2.1mm polar endcapped column is a popular choice for liquid chromatography (LC) applications due to its excellent chromatographic performance and versatility. Here are some pros and cons of buying this particular column:

1. High efficiency and resolution: The small particle size (5 m) and compact size (50mm length) of this column result in high efficiency and excellent resolution, making it suitable for complex sample analysis and challenging separations.

2. Polar endcapped: The polar endcapped stationary phase provides increased separation efficiency and selectivity for polar and ionizable compounds, making it particularly useful for analyzing pharmaceuticals, biomolecules, and environmental samples.

3. Compatibility: The column is compatible with various LC systems and mobile phases, making it a versatile option for a wide range of applications.

4. Robustness: The Hypersil Gold C18 stationary phase is known for its excellent chemical and mechanical stability, ensuring consistent and reliable performance over time.

5. Availability and support: Thermo Fisher Scientific is a reputable and reliable supplier of LC columns, and the Hypersil Gold AQ C18 column is widely used and supported by the scientific community, making it easy to find information and troubleshooting resources.

1. Cost: The Thermo Scientific Hypersil Gold AQ C18 50x2.1mm polar endcapped column is a high-performance column, and the price reflects its advanced features and capabilities.

2. Size: The small size of the column may limit the amount of sample that can be injected, making it less suitable for high-throughput or large-scale analyses.

3. Compatibility with certain mobile phases: Some mobile phases, such as those containing strong acids or bases, may require additional column conditioning or modification to ensure optimal performance.

In conclusion, the Thermo Scientific Hypersil Gold AQ C18 50x2.1mm polar endcapped column is a high-performance LC column with excellent separation efficiency, selectivity, and versatility. While it comes with a higher price tag and may not be suitable for large-scale analyses, its robustness, availability, and compatibility with a wide range of applications make it a valuable investment for laboratories and research institutions focused on complex sample analysis and challenging separations.

Recommendation: If you require a high-performance LC column for complex sample analysis and challenging separations, the Thermo Scientific Hypersil Gold AQ C18 50x2.1mm polar endcapped column is an excellent choice. However, if you are working on a tight budget or require a larger column for high-throughput analyses, you may consider alternative columns with smaller particle sizes or larger column sizes that offer similar separation efficiency and selectivity at a lower cost.

Details:

Scalability: The Hypersil GOLD family is designed to scale from UHPLC 1.9 um preoperative HPLC particle sizes. Peak Shape: Built on ultra pure silica to minimize peak tailing and provide high sensitivity for routine or demanding LC/MS workflows. Polar Analyse Retention: Features a proprietary polar end capping that allows the C18 phase to operate effectively in highly aqueous environments without collapse. This specific model is a 50 X 2.1mm, Column with 5um, Particle size, Optimized for High-Efficiency Separations even in 100% Aqueous mobile phases.

New out of Box Condition, Thermo Hypersil Gold aQ C18 50x2.1mm Polar Endcapped HPLC Column Part No: 25305-052130, Its a GOLD designed for the retention and resolution Analyses.

part #: 25305052130 prices

• $195.00-$395.00

specifications labequipi:

• brand: Thermo Scientific
• mpn: 25305-052130
• country of origin: United States
• intended use/discipline: Hplc Column

returns labequipi:

• paid by: Seller
• time: 30 Days
• method: Money back
• policy: Returns Accepted

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• other
• wallet: Google-pay
• credit card: Diners-club

general labequipi:

• Healthcare, Lab Dental > Medical Lab Equipment, Devices > Other Medical Lab Equipment
• condition: New Open box

seller labequipi:

• rating: 99.2%
• city: San Jose, California
• # reviews: 2752

offer labequipi:

• best offers: True
• availability: In Stock
• started: March 25, 2026
• quantity: 1
• options: Ship-to-home
• sold: 0

shipping labequipi:

• type: Fixed
• cost: $0.00
• transit: 4-8 Days
• class: Standard
• service: USPS Ground Advantage
• carrier: USPS

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