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THERMO SCIENTIFIC 25402-102130 Hypersil Uhplc Hplc Column 100X 2.1MM 1.9

25402-102130 Thermo Scientific Hypersil Gold Pfp 100x 2.1mm 1.9 M Uhplc / Hplc Column

( Brand: Thermo Scientific ), ( Manufacturer Part Number: 25402-102130 ), ( Country Of Origin: United States ), ( Intended Use/discipline: Uhplc / Hplc Column )

Review THERMO SCIENTIFIC Hypersil Gold Pfp 100x 2.1mm 1.9 Uhplc Hplc Column

The Thermo Scientific Hypersil Gold 100x 2.1mm 1.9 um HPLC column is a high-performance liquid chromatography (HPLC) column designed for use in laboratories and research applications. This particular column, with the part number 25402-102130, is part of the Hypersil Gold series, which is known for its exceptional chromatographic performance and versatility.

The column features a 100 pore size and a particle size of 1.9 um. The small particle size allows for increased efficiency and improved resolution, making it an excellent choice for separating complex mixtures. With a length of 2.1mm and an inner diameter of 2.1mm, this short, narrow-bore column is well-suited for use with modern HPLC systems and autosamplers.

The stationary phase of the Hypersil Gold 100x 2.1mm 1.9 um column is made of gold, which provides several advantages over traditional silica-based columns. Gold is chemically inert, ensuring that it does not interact with the analytes being separated. It also exhibits unique selectivity properties, making it an excellent choice for the separation of chiral compounds.

The Hypersil Gold column is packed with a unique, proprietary silica material that has been modified with a thin gold film. The gold film enhances the column's chromatographic performance and stability, making it a reliable and consistent tool for separating a wide range of compounds.

The Hypersil Gold 100x 2.1mm 1.9 um column is compatible with a broad range of mobile phases, including water, acetonitrile, methanol, and acids or bases. It can be used in both normal-phase and reversed-phase separations, making it a versatile and valuable addition to any HPLC laboratory.

This Thermo Scientific column is designed for use with high-pressure HPLC systems and can operate at pressures up to 600 bar (8700 psi). The column is also suitable for use with gradient elution methods and can be easily integrated with autosamplers for automated sample preparation and analysis.

The Hypersil Gold 100x 2.1mm 1.9 um column is delivered in a protective sleeve to ensure safe handling and transport. The column is also supplied with a stainless-steel guard column to protect the analytical column from contamination during sample preparation and loading.

In summary, the Thermo Scientific Hypersil Gold 100x 2.1mm 1.9 um HPLC column is a high-performance, versatile, and chemically inert column that is well-suited for use in a variety of HPLC applications. Its small particle size, gold stationary phase, and exceptional chromatographic performance make it an essential tool for separating complex mixtures and chiral compounds in laboratories and research environments.

Considerations and Recommendation for Purchasing a Thermo Scientific Hypersil 100x 2.1mm 1.9 m UHPLC Column (25402-102130)

Introduction:

The Thermo Scientific Hypersil 100x 2.1mm 1.9 m UHPLC Column (product code: 25402-102130) is a popular choice for ultra-high-performance liquid chromatography (UHPLC) applications due to its high efficiency, narrow bore size, and small particle size. In this analysis, we will discuss the advantages and disadvantages of buying this column to help you make an informed decision.

Pros:

1. High Efficiency: The small particle size (1.9 m) and narrow bore size (2.1 mm) of this column result in increased efficiency and faster separation times for complex mixtures.

2. Improved Resolution: The high efficiency of the column leads to better peak separation and increased sensitivity, allowing for the detection of trace components in a sample.

3. Versatility: This column can be used for various applications, including reversed-phase, normal-phase, and ion-exchange chromatography.

4. Durability: The Hypersil material is known for its resistance to harsh conditions, enabling the column to handle a wide range of mobile phases and pH levels.

5. Compatibility: Thermo Scientific columns are compatible with various UHPLC systems, including the Vanquish, Accela, and Dionex UltiMate systems, making it a versatile option for laboratories.

Cons:

1. Cost: The Thermo Scientific Hypersil 100x 2.1mm 1.9 m UHPLC Column is a premium product, and the cost may be a concern for some laboratories.

2. Limited Sample Loading Capacity: The narrow bore size and small particle size of the column limit the sample loading capacity, requiring smaller injection volumes.

3. Requires Proper Handling: The small particle size of the column increases the risk of column damage during handling and preparation, necessitating proper care and maintenance.

Conclusion:

The Thermo Scientific Hypersil 100x 2.1mm 1.9 m UHPLC Column (25402-102130) is a high-performance column that offers several advantages, including improved efficiency, resolution, versatility, durability, and compatibility. However, its cost, limited sample loading capacity, and the need for proper handling may be potential drawbacks for some laboratories. Ultimately, the decision to purchase this column depends on the specific requirements and budget of your laboratory.

Recommendation:

If your laboratory demands high-performance UHPLC separations, the Thermo Scientific Hypersil 100x 2.1mm 1.9 m UHPLC Column is a recommended choice due to its superior efficiency, resolution, and versatility. To mitigate the cost concern, consider purchasing in bulk or looking for alternative column suppliers. Proper handling and maintenance will also ensure the longevity of the column.

Details:

Used Good Working Condition, Thermo Hypersil GOLD PFP 100x 2.1mm 1.9 m UHPLC / HPLC Column, Part No: 25402-102130, Its a High-Performance Column designed for both Ultra-High Pressure and Conventional Liquid Chromatography. It features a PFP stationary phase that provides alternative selectivity to standard C18 Columns, particularly for Hallucinated and Polar Compounds. NOTICE: Multi-Quantity are avail, pictures show one of the actual units, all in similar conditions. Unique Selectivity: The PFP phase uses fluorine atoms to enhance pi-pi interactions with aromatic molecules, making it ideal for separating positional isomers of hallucinated compounds and difficult-to-resolve polar mixtures.

Excellent Peak Shape: designed to significantly reduce peak tailing, which improves sensitivity and allows for more accurate integration of low-concentration analyses. UHPLC Compatibility:The 1.9 m particle size enables high-throughput screening and ultra-high resolution while maintaining pressure within ranges manageable for many modern HPLC systems.

part #: 25402102130 prices

  • $195.00-$595.00

specifications labequipi:

  • brand: Thermo Scientific
  • mpn: 25402-102130
  • country of origin: United States
  • intended use/discipline: Uhplc / Hplc Column

general labequipi:

  • Healthcare, Lab Dental > Medical Lab Equipment, Devices > Other Medical Lab Equipment
  • condition: New Open box

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  • started: April 9, 2026
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country of origin: united states, intended use/discipline: uhplc / hplc column,
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2 offers $195.00–$595.00 USD
  • New – Open box. Offer #1 priced at $595.00 + $0.00 shipping estimate = $595.00* total. "New out of Box Condition". Thermo Hypersil GOLD PFP 100x 2.1mm 1.9 m UHPLC / HPLC Column.FREE SHIPPING
  • Used. Offer #2 priced at $195.00 + $0.00 shipping estimate = $195.00* total. NOTICE: Multi-Quantity are avail, pictures show one of the actual units, all are in similar conditions.FREE SHIPPING

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