BIO-RAD 670BR0147 Proteon Protein Interaction XPR36 Biorad
( Brand: Bio-rad ), ( Manufacturer Part Number: 670BR0147 ), ( Model: XPR36 )
Review BIO RAD Biorad Proteon Protein Interaction Array System
The Bio-Rad Protein Interaction Analysis System, specifically model number 670BR0147, is a powerful and versatile tool designed for the qualitative and quantitative analysis of protein-protein interactions. This system, marketed under the brand name Bio-Rad Proteon XPR36, employs a surface plasmon resonance (SPR) biosensor technique, which allows real-time monitoring of binding events between proteins.
At the heart of this system is the Proteon XPR36 SPR instrument, which features an intuitive user interface, automated data evaluation, and the ability to conduct multiple experiments simultaneously. The system is capable of analyzing a wide range of interactions, including those involving small and large molecules, as well as interactions that occur under various pH and temperature conditions.
The 670BR0147 kit includes a CM5 sensor chip, which is pre-functionalized with a carboxymethyl dextran (CMD) layer. This layer provides a stable and hydrophilic surface for the immobilization of capture molecules, such as antibodies, proteins, or small molecules, via amine coupling. Once capture molecules are immobilized, the system can be used to analyze interactions with analytes, or test proteins, by passing them over the sensor chip surface in a buffer solution.
The Proteon XPR36 system offers several advantages over other protein interaction analysis methods. For instance, it allows for real-time monitoring of binding events, providing valuable kinetic data, such as association and dissociation rates. Additionally, the system can be used to measure binding affinities, calculating dissociation constants (Kd values), and to evaluate the specificity of binding interactions.
The 670BR0147 kit comes with the necessary reagents and consumables for performing a variety of experiments, including direct binding, competition, and kinetic studies. It also includes the Proteon Manager software, which facilitates data acquisition, analysis, and reporting.
In summary, the Bio-Rad Proteon XPR36 Protein Interaction Analysis System (model 670BR0147) offers a robust and versatile platform for studying protein-protein interactions, featuring real-time monitoring capabilities, automated data evaluation, and the ability to analyze a wide range of interactions. The system's intuitive user interface, automated data analysis, and comprehensive software make it an invaluable tool for researchers in the fields of biochemistry, pharmaceuticals, and proteomics.
A Comprehensive Analysis of buying a Bio-Rad 670BR0147 Proteon XPR36 Protein Interaction Analyzer
The Bio-Rad 670BR0147 Proteon XPR36 is a state-of-the-art protein interaction analyzer designed for high-throughput screening and analysis of protein-protein interactions. Here is a balanced assessment of the pros and cons of investing in this instrument.
Pros:1. High-throughput capability: The Proteon XPR36 can process up to 144 samples in a single run, significantly reducing the time and resources required for large-scale protein interaction studies.
2. Sensitivity and specificity: This instrument offers high sensitivity and specificity for detecting protein-protein interactions, enabling researchers to gain a deeper understanding of complex biological systems.
3. Versatile sample input: The Proteon XPR36 supports various sample types, including purified proteins, cell lysates, and membrane proteins, making it a versatile tool for researchers working on a wide range of projects.
4. User-friendly interface: The analyzer comes with an intuitive software interface, making it easier for researchers to design experiments, analyze data, and interpret results.
5. Integration with other platforms: The Proteon XPR36 can be integrated with other Bio-Rad and third-party instruments, allowing for seamless data transfer and streamlined workflows.
Cons:1. High investment cost: The Protein XPR36 is a significant investment for any research lab, with a high upfront cost that may be a barrier for smaller institutions or researchers with limited budgets.
2. Requires specialized expertise: Operating and maintaining the Proteon XPR36 requires a certain level of expertise, which may necessitate hiring or training dedicated staff or collaborating with external service providers.
3. Lengthy assay development: Developing assays for the Proteon XPR36 can be time-consuming and may require extensive optimization, particularly for membrane protein interactions.
4. Consumables cost: The Proteon XPR36 uses consumables that can be expensive, adding to the overall cost of operation for the instrument.
5. Limited throughput for some applications: While the Proteon XPR36 offers high-throughput capabilities, it may not be suitable for applications that require extremely high throughput or screening large libraries of compounds.
Conclusion:The Bio-Rad 670BR0147 Proteon XPR36 Protein Interaction Analyzer offers numerous advantages for researchers seeking to study protein-protein interactions at a high throughput. Its sensitivity, specificity, and versatility make it an invaluable tool for understanding complex biological systems. However, its high investment cost, requirement for specialized expertise, and consumables expenses are significant considerations.
Recommendation:If your research focuses on protein-protein interactions and you have the necessary resources, the Proteon XPR36 is an excellent investment. It can help streamline your workflows, increase throughput, and provide valuable insights into complex biological systems. However, if you are working with a limited budget or require a more affordable solution, consider alternative methods or collaborating with service providers to access the Proteon XPR36's capabilities on a project-by-project basis.
Details:
Compatibility issues are not considered Dead On Arrival. We currently offer FedEx and USPS on most orders. This unit is being sold AS-IS and USED. Contact the carrier for further help with delivery issues.
See photos for more details. Our Shipping cutoff is at 2 pm PST. Shipping options are shown on the item page in shipping calculator. Power Tested Otherwise this units are in good cosmetic condition.
BIORAD ProteOn PROTEIN INTERACTION ARRAY SYSTEM, Pulled from a working environment. Please reach out with any questions. This listing is for what pictured only.
part #: 670br0147 prices
- $475.00-$1299.99
specifications labequipi:
- brand: Bio-rad
- mpn: 670br0147
- model: Xpr36
payments labequipi:
- wallet: Google-pay
- credit card: Discover
- other
shipping labequipi:
general labequipi:
- Healthcare, Lab Dental > Medical Lab Equipment, Devices > Other Medical Lab Equipment
- condition: Used
seller labequipi:
- rating: 100.0%
- city: Fremont, California
- # reviews: 17
returns labequipi:
- method: Money back
- time: 30 Days
- paid by: Buyer
- policy: Returns Accepted
offer labequipi:
- options: Ship-to-home
- quantity: 1
- availability: In Stock
- sold: 0
- started: March 31, 2025
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