
( Brand: Oxford ), ( Manufacturer Part Number: NMR-400 ), ( Part Type: Tank )
The Oxford NMR-400 CryoProbe is a top-of-the-line Nuclear Magnetic Resonance (NMR) cryogenic probe designed for high-performance, high-resolution NMR experiments. This particular model is the NMR-400 variant, which is compatible with 400 MHz NMR spectrometers.
The probe features a superconducting magnet with a bore size of 50 mm, making it suitable for a wide range of sample types including small to medium-sized organic, inorganic and biological samples. The probe is equipped with a triple resonance (1H, 13C, and 15N) probehead, enabling multi-nuclear experiments for enhanced molecular recognition.
One of the most distinctive features of this probe is its CryoProbe technology. The probe is cooled down to cryogenic temperatures, which reduces the sample temperature to near absolute zero degrees Celsius, resulting in superior signal-to-noise ratio and increased spectral resolution. This, in turn, makes it possible to acquire high-quality NMR data, even from challenging samples, with minimal signal broadening and distortion.
The NMR-400 CryoProbe also incorporates several advanced features, such as frequency-agile broadband probes, which provide excellent sensitivity and allow for easy switching between different nuclei and experiments. The probe's temperature stability ensures that constant and precise temperature conditions are maintained throughout the experiment, contributing to signal stability and the accurate determination of spectroscopic parameters.
The probe's ergonomic design includes a large, user-friendly front panel with intuitive controls, making operation efficient and stress-free. Additionally, it is designed for easy prob head replacement, allowing users to perform different types of experiments with minimal downtime.
Overall, the Oxford NMR-400 CryoProbe is an ideal choice for researchers and technicians working with a 400 MHz NMR spectrometer who are seeking high-resolution, high-sensitivity data for their samples, particularly those that have limited solubility or dynamic properties. With its innovative cryogenic technology, advanced features, and user-friendly design, this probe offers the best possible NMR experience for conducting experiments with confidence and accuracy.
The Oxford Instruments NMR-400 CryoProbe with a 4525 cryogen-free refrigerator is a high-performance Nuclear Magnetic Resonance (NMR) system designed for advanced research in various industries, including pharmaceuticals, materials science, and academia. This system's primary advantage is its use of cryoprobes and a cryogen-free refrigerator, which can lead to enhanced spectral resolution and sensitivity. However, like any complex scientific instrument, there are pros and cons to consider before making a purchase.
Pros:1. Enhanced NMR Performance: The NMR-400 system's use of a high-performance cryoprobe provides several benefits, including improved spectral resolution and sensitivity over traditional room temperature probes. The solid-state cryotemperatures allow for reduced sample heating and longer experiment times. Furthermore, the system's automatic tuning and matching capabilities make sample preparation significantly more effortless.
2. Increased Productivity: The NMR-400 cryoprobe's fast magnet recording capabilities enable rapid data acquisition and shorter experiment times. Additionally, the system's probe design increases the spectral width and allows for more complex experiments (e.g., 2D, 3D) and larger sample throughput.
3. Minimized Maintenance: With the Oxford Instruments NMR-400's 4525 cryogen-free refrigerator, scheduling maintenance downtimes is greatly reduced, making the instrument ideal for laboratories with demanding schedules. The need for liquid helium refills is eliminated, thereby reducing operational costs significantly. Moreover, the system's air-cooled shielded cabling provides elimination of the need for liquid nitrogen and is more environmental-friendly.
4. Versatility: The NMR-400 system's capability to accommodate a wide range of sample sizes and container types makes it a versatile tool for various applications, from micrograms to grams. Furthermore, the system's compatibility with various solvents, including deuterated and non-deuterated, further enhances its versatility.
5. User-friendly: The system's high-resolution console and intuitive Touchscreen interface provide users with easy-to-use software and data analysis tools. The software is customizable and feature-rich, making it suitable for both novice and experienced researchers.
Cons:1. Expensive: With its advanced features and high-performance capabilities, the Oxford Instruments NMR-400 CryoProbe system with a 4525 cryogen-free refrigerator comes with a steep price tag. Research laboratories and institutions with significant research budgets and prioritization of high-resolution NMR experiments will find this system a valuable investment.
2. Requires Expertise: Operating the NMR-400 system and its accompanying software requires a high level of expertise. It is crucial for laboratories to have experienced NMR specialists on staff to ensure proper usage, maintenance, and troubleshooting.
3. Limited Sample Size: Although the NMR-400 system's probe design can accommodate a range of sample sizes, there may still be limitations on the total sample volume compared to other traditional NMR systems. This may not be an issue for most research applications but could be a limitation for specific projects dealing with larger sample volumes.
4. Need for Upgrades: The NMR-400 system's advanced features may require ongoing upgrades and software updates to leverage new techniques and experiments. Upgrades can incur additional costs and require the assistance of technical support.
Conclusion:The Oxford Instruments NMR-400 CryoProbe system with a 4525 cryogen-free refrigerator provides superior NMR performance with enhanced spectral resolution, sensitivity, and productivity. It minimizes maintenance requirements and offers versatility and user-friendly operation. However, its high cost, demand for expertise, and limited sample size are factors that potential buyers should consider before making a purchasing decision.
Recommendation:If your laboratory places a high priority on cutting-edge NMR research and is able to invest significant resources in high-performance instrumentation, the Oxford Instruments NMR-400 CryoProbe with a 4525 cryogen-free refrigerator is a valuable investment. For laboratories with limited resources or projects requiring larger sample volumes, other traditional NMR systems may be a more suitable alternative.
Complete address phone # Acquired from a reliable source. Commercial or residential location, Some cosmetic wear.
COMES AS SHOWN. No means to test. High cost, high value equipment for a fraction of the new /replacement price. Used items have a 30-day return.
No accessories including standard power cord/cable.